There ’s no doubt that arrest high can make you do some reasonably silent poppycock , although the scientific community stay break up over whether or not smoking too many joints make lasting cognitive disability . The late research into this controversial subject has find evidence of a connective between exuberant cannabis usance and decreased dopamine level in the brain , which could in turn lead to memory , attention , and trouble - solving deficit .
Dopamineis a neurotransmitter that play a fundamental persona in the brain ’s so - address reward center , and is released in response to pleasurable input like eat on cake , give birth sex , and take drugs . This is what makes many drug so addictive ( and coat so irresistible ) , although inquiry hint that unreasonable consumption of these heart cause a dopamine unbalance , with broken concentrations of the chemical being released in parts of the mentality such as the corpus striatum .
significantly , dopamine deficits in the corpus striatum have been associated withreduced cognitive public presentation . turn over that THC – the alive ingredient in marijuana – is know to energize dopamine neuron throughout the brain , lead researcher Anissa Abi - Darghamexplainedthat “ it is authoritative to look more closely at the potentially habit-forming effect of hemp on key area of the brain . ”
To do so , she and a group of colleagues used a technique call positron emission tomography ( PET ) to examine the levels of Dopastat release in the striatum of 11 cannabis - dependent mass after welcome a superman of unwritten pep pill , which stimulates the brain to give up the neurotransmitter . The answer – which are published in the journalMolecular Psychiatry – betoken that , compare to non - dependent subjects , these player did indeed exhibit reduced Intropin levels .
Dopamine plays a cardinal role in the mentality ’s reinforcement system . Zerbor / Shutterstock
To research the encroachment of this finding , the researchers then subjected all participants to a series of tests project to assess their cognitive functioning . Those with cannabis dependence achieved worse scores for computer memory and care than non - dependent player , lead the study writer to remark that “ low dopamine release may contribute to the disconfirming working impact of inveterate hemp substance abuser . ”
However , the investigator also point out that they “ can not show a causal relationship ” between cannabis usage and Intropin deficit , explaining that they ca n’t be certain “ whether decreased Intropin was a preexisting condition or the solution of labored marijuana use . ”
Taking their investigation a step further , the study authors also measured layer of another neurotransmitter calledglutamatein a genius neighborhood called the genus Hippocampus . In schizophrenic , elevated glutamate levels in this part of the brain are known to negatively affect Dopastat levels , ensue in a routine of psychopathological symptoms .
reach that a radio link between excessive cannabis use andschizophreniahas previously been suggested , the investigator hypothesized that the dopamine deficits experienced by even stoners may be modulated by glutamate , thereby confirming this contact . However , they did not observe any mansion of glutamate imbalances in the hippocampus , and therefore found no evidence of any connectedness between grass smoke and schizophrenia .
While the results of this enquiry are not entirely conclusive , they do shed lighting on some of the potential dangers of undue cannabis use , advise that it may be well to just beat to patty .
