David Spadeis honoring his sister-in-law and designerKate Spadeafter hersuicideat age 55.

PEOPLE exclusively confirms the actor and comedian, 53, has made a $100,000 donation to theNational Alliance on Mental Illness (NAMI).

“More people suffer from mental health issues than we may realize but no one should ever feel ashamed to reach out for support,” Spade says.

“If you or anyone you know is in need of help or guidance please contact the national suicide prevention hotline at 800-273-8255 or go to nami.org to learn more and help those who may be in need,” he adds.

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Slim Aarons Photography Exhibit Curated by Kate Spade at Fred Segal Caf?

On June 5, Kate’s family, friends and fans were shocked to learn a housekeeper arrived to find Kate alone and unresponsive in the bedroom of her Manhattan apartment. The New York City’s medical examiner’s officeofficially declared the designer’s death a suicidetwo days later.

Her husband, Andy, who is David’s older brother,revealed on the day of her deaththat Kate had been in treatment for depression and anxiety. He also confirmed the couple’s separation, noting that he had moved out 10 months earlier to an apartment several blocks away, where daughter Frances Beatrix, 13, spent half her time.

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“Kate suffered from depression and anxiety for many years. She was actively seeking help and working closely with her doctors to treat her disease, one that takes far too many lives. We were in touch with her the night before and she sounded happy,” Andy, 56, said in astatement.

“There was no indication and no warning that she would do this. It was a complete shock. And it clearly wasn’t her. There were personal demons she was battling,” the father of one said.

Kate’s loved ones continue to honor her legacy while trying to understand the pain that led to her death.

“We knew Kate had her problems and demons,” one friend tells PEOPLE in this week’s cover story. “But no one would have ever expected her to do this.”

For PEOPLE’s tribute to two icons: Talent & Tragedy, pick up this week’s issue, on newsstands Friday.

Three days after Kate’s death, David returned to the stage when he performed hisfirst stand-up comedy setat the Brea Improv Comedy Club in Brea, California.

“Thank you for coming. It was a rough week, but I didn’t want to cancel and I appreciate you all coming out here,” he said, according to E! News.

“And if my jokes don’t work then I get sort of a free pass,” he joked. “Thank you for coming out, I appreciate it.”

WATCH: David Spade Breaks His Silence After Sister-in-Law Kate Spade’s Death: ‘I Still Can’t Believe It’

David also previouslypaid tributeto the designer, just hours after news of her death was made public.

“Fuzzy picture but I love it. Kate and I during Christmas family photos. We had so much fun that day. She was so sharp and quick on her feet.She could make me laugh so hard,” he captioned one of his favorite photos of Kate.

“I still can’t believe it. It’s a rough world out there people, try to hang on,” David added.

Sharing asecond tribute on Twitter, he wrote, “Katy at my book signing. I love this pic of her. So pretty. I don’t think everyone knew how f–king funny she was…”

If you or someone you know is considering suicide, please contact the National Suicide Prevention Lifeline at 1-800-273-TALK (8255), text “help” to theCrisis Text Lineat 741-741 or go tosuicidepreventionlifeline.org.

source: people.com